High-throughput saturation mutagenesis generates a high-affinity antibody against SARS-CoV-2 variants using protein surface display assay on a human cell

As new mutations continue to emerge, the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus to evade the human immune system and neutralizing antibodies remains a huge challenge for vaccine development and antibody research. The majority of neutralizing antibodies have red...

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Detalles Bibliográficos
Autores principales: Yang, Ye, Liu, Shuo, Luo, Yufeng, Wang, Bolun, Wang, Junyi, Li, Juan, Li, Jiaxin, Ye, Buqing, Wang, Youchun, Xi, Jianzhong Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891525/
https://www.ncbi.nlm.nih.gov/pubmed/36724179
http://dx.doi.org/10.1371/journal.ppat.1011119

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