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Big data mining, rational modification, and ancestral sequence reconstruction inferred multiple xylose isomerases for biorefinery
The isomerization of xylose to xylulose is considered the most promising approach to initiate xylose bioconversion. Here, phylogeny-guided big data mining, rational modification, and ancestral sequence reconstruction strategies were implemented to explore new active xylose isomerases (XIs) for Sacch...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891696/ https://www.ncbi.nlm.nih.gov/pubmed/36724227 http://dx.doi.org/10.1126/sciadv.add8835 |