Cargando…
GluA3 subunits are required for appropriate assembly of AMPAR GluA2 and GluA4 subunits on cochlear afferent synapses and for presynaptic ribbon modiolar–pillar morphology
Cochlear sound encoding depends on α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), but reliance on specific pore-forming subunits is unknown. With 5-week-old male C57BL/6J Gria3-knockout mice (i.e., subunit GluA3(KO)) we determined cochlear function, synapse ultrastructure,...
Autores principales: | Rutherford, Mark A, Bhattacharyya, Atri, Xiao, Maolei, Cai, Hou-Ming, Pal, Indra, Rubio, Maria Eulalia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891727/ https://www.ncbi.nlm.nih.gov/pubmed/36648432 http://dx.doi.org/10.7554/eLife.80950 |
Ejemplares similares
-
Expression and Interaction Proteomics of GluA1- and GluA3-Subunit-Containing AMPARs Reveal Distinct Protein Composition
por: van der Spek, Sophie J. F., et al.
Publicado: (2022) -
Postsynaptic VAMP/Synaptobrevin Facilitates Differential Vesicle Trafficking of GluA1 and GluA2 AMPA Receptor Subunits
por: Hussain, Suleman, et al.
Publicado: (2015) -
The GluA1 AMPAR subunit is necessary for hedonic responding but not hedonic value in female mice
por: Strickland, Jasmin A., et al.
Publicado: (2021) -
Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex
por: Toyoda, Hiroki, et al.
Publicado: (2009) -
Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit
por: Parkinson, Gabrielle T., et al.
Publicado: (2018)