Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesis

Eyes absent homologue 4 (EYA4) is silenced in pancreatic ductal adenocarcinoma (PDAC) and functions as a tumor suppressor to restrain PDAC development, albeit the molecular mechanism underlying its downregulation remains enigmatic. Methods: Functional studies were determined by immunohistochemistry...

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Detalles Bibliográficos
Autores principales: Jia, Yu, Li, Hui-Yan, Wang, Jue, Chen, Xing, Lou, Lu, Wei, Yan-Yan, Wang, Ying, Mo, Shi-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891873/
https://www.ncbi.nlm.nih.gov/pubmed/36741265
http://dx.doi.org/10.7150/jca.79905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891873/
https://www.ncbi.nlm.nih.gov/pubmed/36741265
http://dx.doi.org/10.7150/jca.79905

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