Cargando…

The Role of CTNNA1 in Malignancies: An Updated Review

Catenin alpha 1 (CTNNA1), encoding α-catenin, is involved in several physiological activities, such as adherens junction synthesis and signal transduction. Recent studies have suggested additional functions for CTNNA1 malignancies. This review systematically summarizes the varying functions of CTNNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jinhua, Wang, Huihui, Xu, Yuting, Li, Chunhua, Lv, Xinyue, Han, Xintong, Chen, Xiaochun, Chen, Yu, Yu, Zhiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891874/ https://www.ncbi.nlm.nih.gov/pubmed/36741258 http://dx.doi.org/10.7150/jca.79236

Ejemplares similares

Recent Updates on the Role of the MicroRNA-10 Family in Gynecological Malignancies
por: Li, Chunhua, et al.
Publicado: (2022)

Clinical and Genetic Findings in CTNNA1-Associated Macular Pattern Dystrophy
por: Tanner, Alexander, et al.
Publicado: (2021)

The application of HER2 and CD47 CAR-macrophage in ovarian cancer
por: Chen, Yizhao, et al.
Publicado: (2023)

CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425
por: He, Bing, et al.
Publicado: (2016)

α-E-Catenin (CTNNA1) Inhibits Cell Proliferation, Invasion and EMT of Bladder Cancer
por: Chi, Qiang, et al.
Publicado: (2020)

Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer by downregulating its cognate gene CTNNA1 expression
por: Chen, Xiangjian, et al.
Publicado: (2016)

Novel somatic variants in CTNNA1 gene in Iranian patients with diffuse gastric cancer
por: Naghi Vishteh, Mohadeseh, et al.
Publicado: (2021)

Role of germline aberrations affecting CTNNA1, MAP3K6 and MYD88 in gastric cancer susceptibility
por: Weren, Robbert D A, et al.
Publicado: (2018)

Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity
por: Saksens, Nicole T.M., et al.
Publicado: (2015)

The role of a key transcription factor PU.1 in autoimmune diseases
por: Fang, Yilong, et al.
Publicado: (2022)

Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3
por: Reitz, Cristine J., et al.
Publicado: (2023)

A CTNNA3 compound heterozygous deletion implicates a role for αT-catenin in susceptibility to autism spectrum disorder
por: Bacchelli, Elena, et al.
Publicado: (2014)

CTNNA1 hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome
por: Li, Mianyang, et al.
Publicado: (2016)

Loss-of-function variants in CTNNA1 detected on multigene panel testing in individuals with gastric or breast cancer
por: Clark, Dana Farengo, et al.
Publicado: (2020)

Frequency of CDH1, CTNNA1 and CTNND1 Germline Variants in Families with Diffuse and Mixed Gastric Cancer
por: Guerra, Joana, et al.
Publicado: (2023)

Analysis of Single Nucleotide Polymorphisms of STK32B, PPARGC1A and CTNNA3 Gene With Sporadic Parkinson's Disease Susceptibility in Chinese Han Population
por: Shi, Chang-he, et al.
Publicado: (2018)

No rare deleterious variants from STK32B, PPARGC1A, and CTNNA3 are associated with essential tremor
por: Houle, Gabrielle, et al.
Publicado: (2017)

Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking
por: Terracciano, A, et al.
Publicado: (2011)

CircCTNNA1 is Upregulated in Mantle Cell Lymphoma and Predicts Poor Survival by Sponging miR-34a to Increase Cell Proliferation
por: Lu, Cong, et al.
Publicado: (2022)

CircCTNNA1 acts as a ceRNA for miR-363-3p to facilitate the progression of colorectal cancer by promoting CXCL5 expression
por: Zhang, Yan, et al.
Publicado: (2021)

Circular RNA circCTNNA1 promotes colorectal cancer progression by sponging miR-149-5p and regulating FOXM1 expression
por: Chen, Pengju, et al.
Publicado: (2020)

An intragenic deletion within CTNNA2 intron 7 in a boy with short stature and speech delay: A case report
por: Paganelli, Valeria, et al.
Publicado: (2017)

Role of RASA1 in cancer: A review and update
por: Zhang, Yanhua, et al.
Publicado: (2020)

CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study
por: Zhang, Yunjun, et al.
Publicado: (2021)

Bi-allelic loss of human CTNNA2, encoding αN-catenin, leads to ARP2/3 over-activity and disordered cortical neuronal migration
por: Schaffer, Ashleigh E., et al.
Publicado: (2018)

First genome-wide association study of esophageal atresia identifies three genetic risk loci at CTNNA3, FOXF1/FOXC2/FOXL1, and HNF1B
por: Gehlen, Jan, et al.
Publicado: (2022)

Update on the role of copanlisib in hematologic malignancies
por: Le, Thuy, et al.
Publicado: (2021)

An Update on the Roles of circRNA-ZFR in Human Malignant Tumors
por: Liu, Lang, et al.
Publicado: (2022)

The role of medical gas in stroke: an updated review
por: Zhang, Ze-Yu, et al.
Publicado: (2019)

Role of human papillomavirus and its detection in potentially malignant and malignant head and neck lesions: updated review
por: Chaudhary, Ajay Kumar, et al.
Publicado: (2009)

Current and Future Roles of Circular RNAs in Normal and Pathological Endometrium
por: Tu, Jiajie, et al.
Publicado: (2021)

Inflammation and pancreatic cancer: An updated review
por: Shadhu, Kamleshsingh, et al.
Publicado: (2019)

An update of oral potentially malignant disorders and their malignant transformation into oral cancers in Taiwan
por: Yang, Po-Yu, et al.
Publicado: (2021)

Submicroscopic deletion of 5q involving tumor suppressor genes (CTNNA1, HSPA9) and copy neutral loss of heterozygosity associated with TET2 and EZH2 mutations in a case of MDS with normal chromosome and FISH results
por: Hemmat, Morteza, et al.
Publicado: (2014)

Systematic Review: An Update on the Spectrum of Urological Malignancies in Lynch Syndrome
por: Huang, Dora, et al.
Publicado: (2018)

The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
por: Tu, Jiajie, et al.
Publicado: (2021)

The role of C-peptide in diabetes and its complications: an updated review
por: Chen, Jintao, et al.
Publicado: (2023)

Antifibrotic Roles of RAAS Blockers: Update
por: Zhang, Ying-Ying, et al.
Publicado: (2019)

Targeting dePARylation selectively suppresses DNA repair–defective and PARP inhibitor–resistant malignancies
por: Chen, Shih-Hsun, et al.
Publicado: (2019)

Potential Roles of Exosomes in the Development and Detection of Malignant Mesothelioma: An Update
por: Munson, Phillip, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_so3p7juo76e297d8b7met3lmud