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The atypical β‐blocker S‐oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model

BACKGROUND: Beta‐blockers and selected stereoisomers of beta‐blockers, like bisoprolol and S‐pindolol (ACM‐001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of oxprenolol in two preclinical models of cancer cachexia—the Yoshida...

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Detalles Bibliográficos
Autores principales: Yuan, Luping, Springer, Jochen, Palus, Sandra, Busquets, Silvia, Jové, Queralt, Alves de Lima Junior, Edson, Anker, Markus S., von Haehling, Stephan, Álvarez Ladrón, Natalia, Millman, Oliver, Oosterlee, Annemijn, Szymczyk, Agata, López‐Soriano, Francisco Javier, Anker, Stefan D., Coats, Andrew J.S., Argiles, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891926/
https://www.ncbi.nlm.nih.gov/pubmed/36346141
http://dx.doi.org/10.1002/jcsm.13116