AMP‐activated protein kinase inhibition in fibro‐adipogenic progenitors impairs muscle regeneration and increases fibrosis

BACKGROUND: Following muscle injury, fibro‐adipogenic progenitors (FAPs) are rapidly activated and undergo apoptosis at the resolution stage, which is required for proper muscle regeneration. When excessive FAPs remain, it contributes to fibrotic and fatty infiltration, impairing muscle recovery. Me...

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Detalles Bibliográficos
Autores principales: Liu, Xiangdong, Zhao, Liang, Gao, Yao, Chen, Yanting, Tian, Qiyu, Son, Jun Seok, Chae, Song Ah, de Avila, Jeanene Marie, Zhu, Mei‐Jun, Du, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891933/
https://www.ncbi.nlm.nih.gov/pubmed/36513394
http://dx.doi.org/10.1002/jcsm.13150

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