Cargando…
Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia
BACKGROUND: Cancer‐associated cachexia (CAC) is a wasting syndrome drastically reducing efficacy of chemotherapy and life expectancy of patients. CAC affects up to 80% of cancer patients, yet the mechanisms underlying the disease are not well understood and no approved disease‐specific medication ex...
Autores principales: | Pototschnig, Isabella, Feiler, Ursula, Diwoky, Clemens, Vesely, Paul W., Rauchenwald, Thomas, Paar, Margret, Bakiri, Latifa, Pajed, Laura, Hofer, Peter, Kashofer, Karl, Sukhbaatar, Nyamdelger, Schoiswohl, Gabriele, Weichhart, Thomas, Hoefler, Gerald, Bock, Christoph, Pichler, Martin, Wagner, Erwin F., Zechner, Rudolf, Schweiger, Martina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891934/ https://www.ncbi.nlm.nih.gov/pubmed/36351437 http://dx.doi.org/10.1002/jcsm.13109 |
Ejemplares similares
-
Iron Regulation: Macrophages in Control
por: Sukhbaatar, Nyamdelger, et al.
Publicado: (2018) -
Adverse cardiac remodeling augments adipose tissue ß-adrenergic signaling and lipolysis counteracting diet-induced obesity
por: Kolleritsch, Stephanie, et al.
Publicado: (2023) -
An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia
por: Xie, Hao, et al.
Publicado: (2022) -
p38 regulates the tumor suppressor PDCD4 via the TSC-mTORC1 pathway
por: Braun, Clarissa, et al.
Publicado: (2021) -
Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation
por: Pajed, Laura, et al.
Publicado: (2019)