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Loss of FoxOs in muscle increases strength and mitochondrial function during aging

BACKGROUND: Muscle mitochondrial decline is associated with aging‐related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. However, disruptions in proteostasis and autophagy are hallmar...

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Detalles Bibliográficos
Autores principales:	Penniman, Christie M., Bhardwaj, Gourav, Nowers, Colette J., Brown, Chandler U., Junck, Taylor L., Boyer, Cierra K., Jena, Jayashree, Fuqua, Jordan D., Lira, Vitor A., O'Neill, Brian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891940/ https://www.ncbi.nlm.nih.gov/pubmed/36442857 http://dx.doi.org/10.1002/jcsm.13124

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