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α‐Synuclein aggregation causes muscle atrophy through neuromuscular junction degeneration
BACKGROUND: Sarcopenia is common in patients with Parkinson's disease (PD), showing mitochondrial oxidative stress in skeletal muscle. The aggregation of α‐synuclein (α‐Syn) to induce oxidative stress is a key pathogenic process of PD; nevertheless, we know little about its potential role in re...
Autores principales: | Yang, Qiumei, Wang, Yanyan, Zhao, Chunsong, Pang, Shimin, Lu, Jing, Chan, Piu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891985/ https://www.ncbi.nlm.nih.gov/pubmed/36416282 http://dx.doi.org/10.1002/jcsm.13123 |
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