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Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center

BACKGROUND: Thoracic mesenchymal hamartomas are rare benign lesions. Rarely symptomatic, they may compress pulmonary parenchyma, leading to respiratory distress. Although spontaneous regression has been documented, the more common outcome is progressive growth. The treatment of choice is en bloc exc...

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Autores principales: Inserra, Alessandro, Martucci, Cristina, Cassanelli, Giulia, Crocoli, Alessandro, Paolantonio, Guglielmo, Gregori, Lorenzo M., Natali, Gian Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892089/
https://www.ncbi.nlm.nih.gov/pubmed/36058941
http://dx.doi.org/10.1007/s00247-022-05498-1
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author Inserra, Alessandro
Martucci, Cristina
Cassanelli, Giulia
Crocoli, Alessandro
Paolantonio, Guglielmo
Gregori, Lorenzo M.
Natali, Gian Luigi
author_facet Inserra, Alessandro
Martucci, Cristina
Cassanelli, Giulia
Crocoli, Alessandro
Paolantonio, Guglielmo
Gregori, Lorenzo M.
Natali, Gian Luigi
author_sort Inserra, Alessandro
collection PubMed
description BACKGROUND: Thoracic mesenchymal hamartomas are rare benign lesions. Rarely symptomatic, they may compress pulmonary parenchyma, leading to respiratory distress. Although spontaneous regression has been documented, the more common outcome is progressive growth. The treatment of choice is en bloc excision of the involved portion of the chest wall, frequently leading to significant deformity. OBJECTIVE: The aim of our study was to describe percutaneous techniques to treat these lesions. MATERIALS AND METHODS: We collected data of children with thoracic mesenchymal hamartomas who were treated at our institution from 2005 to 2020 using various percutaneous techniques. Techniques included radiofrequency thermoablation, microwave thermoablation (microwave thermoablation) and cryoablation. RESULTS: Five children were treated for chest wall hamartomas; one child showed bilateral localization of the mass. Two children underwent microwave thermoablation, one radiofrequency thermoablation and two cryoablation; one child treated with cryoablation also had radiofrequency thermoablation because mass volume increased after the cryoablation procedure. The median reduction of tumor volume was 69.6% (24.0–96.5%). One child treated with microwave thermoablation showed volumetric increase of the mass and underwent surgical removal of the tumor. No major complication was reported. CONCLUSION: Percutaneous ablation is technically feasible for expert radiologists and might represent a valid and less invasive treatment for chest wall chondroid hamartoma, avoiding skeletal deformities.
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spelling pubmed-98920892023-02-03 Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center Inserra, Alessandro Martucci, Cristina Cassanelli, Giulia Crocoli, Alessandro Paolantonio, Guglielmo Gregori, Lorenzo M. Natali, Gian Luigi Pediatr Radiol Original Article BACKGROUND: Thoracic mesenchymal hamartomas are rare benign lesions. Rarely symptomatic, they may compress pulmonary parenchyma, leading to respiratory distress. Although spontaneous regression has been documented, the more common outcome is progressive growth. The treatment of choice is en bloc excision of the involved portion of the chest wall, frequently leading to significant deformity. OBJECTIVE: The aim of our study was to describe percutaneous techniques to treat these lesions. MATERIALS AND METHODS: We collected data of children with thoracic mesenchymal hamartomas who were treated at our institution from 2005 to 2020 using various percutaneous techniques. Techniques included radiofrequency thermoablation, microwave thermoablation (microwave thermoablation) and cryoablation. RESULTS: Five children were treated for chest wall hamartomas; one child showed bilateral localization of the mass. Two children underwent microwave thermoablation, one radiofrequency thermoablation and two cryoablation; one child treated with cryoablation also had radiofrequency thermoablation because mass volume increased after the cryoablation procedure. The median reduction of tumor volume was 69.6% (24.0–96.5%). One child treated with microwave thermoablation showed volumetric increase of the mass and underwent surgical removal of the tumor. No major complication was reported. CONCLUSION: Percutaneous ablation is technically feasible for expert radiologists and might represent a valid and less invasive treatment for chest wall chondroid hamartoma, avoiding skeletal deformities. Springer Berlin Heidelberg 2022-09-05 2023 /pmc/articles/PMC9892089/ /pubmed/36058941 http://dx.doi.org/10.1007/s00247-022-05498-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Inserra, Alessandro
Martucci, Cristina
Cassanelli, Giulia
Crocoli, Alessandro
Paolantonio, Guglielmo
Gregori, Lorenzo M.
Natali, Gian Luigi
Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
title Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
title_full Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
title_fullStr Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
title_full_unstemmed Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
title_short Percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
title_sort percutaneous treatment of chest wall chondroid hamartomas: the experience of a single center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892089/
https://www.ncbi.nlm.nih.gov/pubmed/36058941
http://dx.doi.org/10.1007/s00247-022-05498-1
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