Lysine methyltransferase Kmt2d regulates naive CD8(+) T cell activation-induced survival

Lysine specific methyltransferase 2D (Kmt2d) catalyzes the mono-methylation of histone 3 lysine 4 (H3K4me1) and plays a critical role in regulatory T cell generation via modulating Foxp3 gene expression. Here we report a role of Kmt2d in naïve CD8(+) T cell generation and survival. In the absence of...

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Detalles Bibliográficos
Autores principales: Kim, Jaekwan, Nguyen, Thomas, Cifello, Jeffrey, Ahmad, Raheel, Zhang, Yongqing, Yang, Qian, Lee, Ji-Eun, Li, Xiang, Kai, Yan, De, Supriyo, Peng, Weiqun, Ge, Kai, Weng, Nan-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892454/
https://www.ncbi.nlm.nih.gov/pubmed/36741385
http://dx.doi.org/10.3389/fimmu.2022.1095140

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