GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

In the treatment of most malignancies, radiotherapy plays a significant role. However, the resistance of cancer cells to ionizing radiation (IR) is the main reason for the failure of radiotherapy, which causes tumor recurrence and metastasis. In this study, we confirmed that GPR162, an orphan recept...

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Detalles Bibliográficos
Autores principales: Long, Yao, Guo, Jiaxing, Chen, Jielin, Sun, Jingyue, Wang, Haiyan, Peng, Xin, Wang, Zuli, Lai, WeiWei, Liu, Na, Shu, Long, Chen, Ling, Shi, Ying, Xiao, Desheng, Liu, Shuang, Tao, Yongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892510/
https://www.ncbi.nlm.nih.gov/pubmed/36725837
http://dx.doi.org/10.1038/s41392-022-01224-3

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