Selective Inhibition of PI3K Isoforms in Brain Tumors Suppresses Tumor Growth by Increasing Radiosensitivity

PURPOSE: Glioblastoma (GBM) is a malignant brain tumor with poor prognosis. Radioresistance is a major challenge in the treatment of brain tumors. The development of several types of tumors, including GBM, involves the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway. Upon a...

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Detalles Bibliográficos
Autores principales: Seol, Mi Youn, Choi, Seo Hee, Lee, Ik Jae, Park, Hyung Soon, Kim, Hye Ryun, Kim, Sang Kyum, Yoon, Hong In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892548/
https://www.ncbi.nlm.nih.gov/pubmed/36719022
http://dx.doi.org/10.3349/ymj.2022.0414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892548/
https://www.ncbi.nlm.nih.gov/pubmed/36719022
http://dx.doi.org/10.3349/ymj.2022.0414

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