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Selective Inhibition of PI3K Isoforms in Brain Tumors Suppresses Tumor Growth by Increasing Radiosensitivity
PURPOSE: Glioblastoma (GBM) is a malignant brain tumor with poor prognosis. Radioresistance is a major challenge in the treatment of brain tumors. The development of several types of tumors, including GBM, involves the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway. Upon a...
Autores principales: | Seol, Mi Youn, Choi, Seo Hee, Lee, Ik Jae, Park, Hyung Soon, Kim, Hye Ryun, Kim, Sang Kyum, Yoon, Hong In |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892548/ https://www.ncbi.nlm.nih.gov/pubmed/36719022 http://dx.doi.org/10.3349/ymj.2022.0414 |
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