Single-exonuclease nanocircuits reveal the RNA degradation dynamics of PNPase and demonstrate potential for RNA sequencing

The degradation process of RNA is decisive in guaranteeing high-fidelity translation of genetic information in living organisms. However, visualizing the single-base degradation process in real time and deciphering the degradation mechanism at the single-enzyme level remain formidable challenges. He...

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Detalles Bibliográficos
Autores principales: Yang, Zhiheng, Liu, Wenzhe, Zhao, Lihua, Yin, Dongbao, Feng, Jianfei, Li, Lidong, Guo, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892577/
https://www.ncbi.nlm.nih.gov/pubmed/36725855
http://dx.doi.org/10.1038/s41467-023-36278-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892577/
https://www.ncbi.nlm.nih.gov/pubmed/36725855
http://dx.doi.org/10.1038/s41467-023-36278-6

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