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Single-exonuclease nanocircuits reveal the RNA degradation dynamics of PNPase and demonstrate potential for RNA sequencing

The degradation process of RNA is decisive in guaranteeing high-fidelity translation of genetic information in living organisms. However, visualizing the single-base degradation process in real time and deciphering the degradation mechanism at the single-enzyme level remain formidable challenges. He...

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Detalles Bibliográficos
Autores principales:	Yang, Zhiheng, Liu, Wenzhe, Zhao, Lihua, Yin, Dongbao, Feng, Jianfei, Li, Lidong, Guo, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892577/ https://www.ncbi.nlm.nih.gov/pubmed/36725855 http://dx.doi.org/10.1038/s41467-023-36278-6

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