satuRn: Scalable analysis of differential transcript usage for bulk and single-cell RNA-sequencing applications

Alternative splicing produces multiple functional transcripts from a single gene. Dysregulation of splicing is known to be associated with disease and as a hallmark of cancer. Existing tools for differential transcript usage (DTU) analysis either lack in performance, cannot account for complex exper...

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Detalles Bibliográficos
Autores principales: Gilis, Jeroen, Vitting-Seerup, Kristoffer, Van den Berge, Koen, Clement, Lieven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Method Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892655/
https://www.ncbi.nlm.nih.gov/pubmed/36762203
http://dx.doi.org/10.12688/f1000research.51749.2

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