Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function

The morbidity and mortality of cardiovascular diseases are exceedingly high worldwide. Pathological heart remodeling, which is developed as a result of mitochondrial dysfunction, could ultimately drive heart failure. More recent research target exercise modulation of mitochondrial dysfunction to imp...

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Autores principales: Li, Kunzhe, Wan, Bingzhi, Li, Sujuan, Chen, Zhixin, Jia, Hao, Song, Yinping, Zhang, Jiamin, Ju, Wenyu, Ma, Han, Wang, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892907/
https://www.ncbi.nlm.nih.gov/pubmed/36744035
http://dx.doi.org/10.3389/fphys.2023.1063556
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author Li, Kunzhe
Wan, Bingzhi
Li, Sujuan
Chen, Zhixin
Jia, Hao
Song, Yinping
Zhang, Jiamin
Ju, Wenyu
Ma, Han
Wang, Youhua
author_facet Li, Kunzhe
Wan, Bingzhi
Li, Sujuan
Chen, Zhixin
Jia, Hao
Song, Yinping
Zhang, Jiamin
Ju, Wenyu
Ma, Han
Wang, Youhua
author_sort Li, Kunzhe
collection PubMed
description The morbidity and mortality of cardiovascular diseases are exceedingly high worldwide. Pathological heart remodeling, which is developed as a result of mitochondrial dysfunction, could ultimately drive heart failure. More recent research target exercise modulation of mitochondrial dysfunction to improve heart failure. Therefore, finding practical treatment goals and exercise programs to improve cardiovascular disease is instrumental. Better treatment options are available with the recent development of exercise and drug therapy. This paper summarizes pathological states of abnormal mitochondrial function and intervention strategies for exercise therapy.
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spelling pubmed-98929072023-02-03 Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function Li, Kunzhe Wan, Bingzhi Li, Sujuan Chen, Zhixin Jia, Hao Song, Yinping Zhang, Jiamin Ju, Wenyu Ma, Han Wang, Youhua Front Physiol Physiology The morbidity and mortality of cardiovascular diseases are exceedingly high worldwide. Pathological heart remodeling, which is developed as a result of mitochondrial dysfunction, could ultimately drive heart failure. More recent research target exercise modulation of mitochondrial dysfunction to improve heart failure. Therefore, finding practical treatment goals and exercise programs to improve cardiovascular disease is instrumental. Better treatment options are available with the recent development of exercise and drug therapy. This paper summarizes pathological states of abnormal mitochondrial function and intervention strategies for exercise therapy. Frontiers Media S.A. 2023-01-19 /pmc/articles/PMC9892907/ /pubmed/36744035 http://dx.doi.org/10.3389/fphys.2023.1063556 Text en Copyright © 2023 Li, Wan, Li, Chen, Jia, Song, Zhang, Ju, Ma and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Li, Kunzhe
Wan, Bingzhi
Li, Sujuan
Chen, Zhixin
Jia, Hao
Song, Yinping
Zhang, Jiamin
Ju, Wenyu
Ma, Han
Wang, Youhua
Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function
title Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function
title_full Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function
title_fullStr Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function
title_full_unstemmed Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function
title_short Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function
title_sort mitochondrial dysfunction in cardiovascular disease: towards exercise regulation of mitochondrial function
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892907/
https://www.ncbi.nlm.nih.gov/pubmed/36744035
http://dx.doi.org/10.3389/fphys.2023.1063556
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