Cargando…

Comprehensive analysis of the immune pattern of T cell subsets in chronic myeloid leukemia before and after TKI treatment

BACKGROUND: Immunological phenotypes and differentiation statuses commonly decide the T cell function and anti-tumor ability. However, little is known about these alterations in CML patients. METHOD: Here, we investigated the immunologic phenotypes (CD38/CD69/HLA-DR/CD28/CD57/BTLA/TIGIT/PD-1) of T s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Danlin, Lai, Jing, Lu, Yuhong, Zhong, Jun, Zha, Xianfeng, Huang, Xin, Liu, Lian, Zeng, Xiangbo, Chen, Shaohua, Weng, Jianyu, Du, Xin, Li, Yangqiu, Xu, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893006/ https://www.ncbi.nlm.nih.gov/pubmed/36742315 http://dx.doi.org/10.3389/fimmu.2023.1078118

Ejemplares similares

Re-balance of memory T cell subsets in peripheral blood from patients with CML after TKI treatment
por: Yao, Danlin, et al.
Publicado: (2017)

Age related human T cell subset evolution and senescence
por: Li, Mingde, et al.
Publicado: (2019)

Increased Expression of TIGIT/CD57 in Peripheral Blood/Bone Marrow NK Cells in Patients with Chronic Myeloid Leukemia
por: Yao, Danlin, et al.
Publicado: (2020)

Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia
por: Zha, Xianfeng, et al.
Publicado: (2012)

Higher TOX Genes Expression Is Associated With Poor Overall Survival for Patients With Acute Myeloid Leukemia
por: Liang, Chaofeng, et al.
Publicado: (2021)

PD-1 and TIGIT Are Highly Co-Expressed on CD8(+) T Cells in AML Patient Bone Marrow
por: Xu, Ling, et al.
Publicado: (2021)

Memory T cells skew toward terminal differentiation in the CD8+ T cell population in patients with acute myeloid leukemia
por: Xu, Ling, et al.
Publicado: (2018)

Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia
por: Wang, Liang, et al.
Publicado: (2010)

Altered expression pattern of miR-29a, miR-29b and the target genes in myeloid leukemia
por: Xu, Ling, et al.
Publicado: (2014)

Single‐Cell RNA‐Seq of T Cells in B‐ALL Patients Reveals an Exhausted Subset with Remarkable Heterogeneity
por: Wang, Xiaofang, et al.
Publicado: (2021)

Single-cell profiling of T cells uncovers a tissue-resident memory-like T-cell subset associated with bidirectional prognosis for B-cell acute lymphoblastic leukemia
por: Lai, Wenpu, et al.
Publicado: (2022)

Persistent donor derived Vδ4 T cell clones may improve survival for recurrent T cell acute lymphoblastic leukemia after HSCT and DLI
por: Xu, Ling, et al.
Publicado: (2016)

Expression patterns of immune checkpoints in acute myeloid leukemia
por: Chen, Cunte, et al.
Publicado: (2020)

Different expression patterns of VISTA concurrent with PD-1, Tim-3, and TIGIT on T cell subsets in peripheral blood and bone marrow from patients with multiple myeloma
por: Huang, Shuxin, et al.
Publicado: (2022)

Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia
por: Huang, Xin, et al.
Publicado: (2015)

BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia
por: Zhong, Mengjun, et al.
Publicado: (2022)

Correction to: BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia
por: Zhong, Mengjun, et al.
Publicado: (2022)

The TKI Era in Chronic Leukemias
por: De Novellis, Danilo, et al.
Publicado: (2021)

Monitoring the Response to Tyrosine Kinase Inhibitor (TKI) Treatment in Chronic Myeloid Leukemia (CML)
por: Haznedaroglu, Ibrahim C.
Publicado: (2014)

Immunosuppressive Cell Subsets and Factors in Myeloid Leukemias
por: Swatler, Julian, et al.
Publicado: (2021)

Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis
por: Liu, Xin, et al.
Publicado: (2023)

Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells
por: Zeng, Chengwu, et al.
Publicado: (2014)

The role of peptide and DNA vaccines in myeloid leukemia immunotherapy
por: Lin, Chen, et al.
Publicado: (2013)

Identification of TCR Vβ11-2-Dβ1-Jβ1-1 T cell clone specific for WT1 peptides using high-throughput TCRβ gene sequencing
por: Zhang, Yikai, et al.
Publicado: (2019)

Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation
por: Shen, Qi, et al.
Publicado: (2013)

A review of the therapeutic role of the new third-generation TKI olverembatinib in chronic myeloid leukemia
por: Qian, Honglan, et al.
Publicado: (2022)

Quality‐of‐life, mental health, and perspective on TKI dose reduction as a prelude to discontinuation in chronic phase chronic myeloid leukemia
por: Chen, Yilin, et al.
Publicado: (2023)

Expression and distribution of PPP2R5C gene in leukemia
por: Zheng, Haitao, et al.
Publicado: (2011)

An observational study on risk of secondary cancers in chronic myeloid leukemia patients in the TKI era in the United States
por: Kumar, Vivek, et al.
Publicado: (2018)

Targeting BCR-ABL-Independent TKI Resistance in Chronic Myeloid Leukemia by mTOR and Autophagy Inhibition
por: Mitchell, Rebecca, et al.
Publicado: (2017)

The evolution of malignant and reactive γδ + T cell clones in a relapse T-ALL case after allogeneic stem cell transplantation
por: Chen, Shaohua, et al.
Publicado: (2013)

Generation of diffuse large B cell lymphoma-associated antigen-specific Vα6/Vβ13+T cells by TCR gene transfer
por: Yin, Qingsong, et al.
Publicado: (2011)

New insights into antigen specific immunotherapy for chronic myeloid leukemia
por: Li, Yangqiu, et al.
Publicado: (2012)

Generation of V α13/β21(+)T cell specific target CML cells by TCR gene transfer
por: Zha, Xianfeng, et al.
Publicado: (2016)

Oligoclonal expansion of TCR Vδ T cells may be a potential immune biomarker for clinical outcome of acute myeloid leukemia
por: Jin, Zhenyi, et al.
Publicado: (2016)

Study of Bone Marrow Lymphocyte Subset in Acute Myeloid Leukemia
por: Dange, Prasad, et al.
Publicado: (2021)

Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia
por: Zeng, Chengwu, et al.
Publicado: (2015)

BCL11B Mutations Are Associated with Higher CD8+ T-Cell Percentage and Favorable Clinical Outcomes in Patients with T-Cell Acute Lymphoblastic Leukemia
por: Chen, Cunte, et al.
Publicado: (2023)

Increased PD-1+Tim-3+ exhausted T cells in bone marrow may influence the clinical outcome of patients with AML
por: Tan, Jiaxiong, et al.
Publicado: (2020)

Importance of TKI treatment duration in treatment-free remission of chronic myeloid leukemia: results of the D-FREE study
por: Yoshida, Chikashi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hlfpmjvqqc13smuhpp33qcscc3