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One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
RATIONALE: Long-term outcomes of patients with coronavirus disease (COVID-19)–related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. OBJECTIVES: To assess physical examination, pulmonary function tests, anxiety, depression, post-traumatic str...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893333/ https://www.ncbi.nlm.nih.gov/pubmed/36150112 http://dx.doi.org/10.1164/rccm.202206-1145OC |
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author | Chommeloux, Juliette Valentin, Simon Winiszewski, Hadrien Adda, Mélanie Pineton de Chambrun, Marc Moyon, Quentin Mathian, Alexis Capellier, Gilles Guervilly, Christophe Levy, Bruno Jaquet, Pierre Sonneville, Romain Voiriot, Guillaume Demoule, Alexandre Boussouar, Samia Painvin, Benoit Lebreton, Guillaume Combes, Alain Schmidt, Matthieu |
author_facet | Chommeloux, Juliette Valentin, Simon Winiszewski, Hadrien Adda, Mélanie Pineton de Chambrun, Marc Moyon, Quentin Mathian, Alexis Capellier, Gilles Guervilly, Christophe Levy, Bruno Jaquet, Pierre Sonneville, Romain Voiriot, Guillaume Demoule, Alexandre Boussouar, Samia Painvin, Benoit Lebreton, Guillaume Combes, Alain Schmidt, Matthieu |
author_sort | Chommeloux, Juliette |
collection | PubMed |
description | RATIONALE: Long-term outcomes of patients with coronavirus disease (COVID-19)–related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. OBJECTIVES: To assess physical examination, pulmonary function tests, anxiety, depression, post-traumatic stress disorder and quality of life at 6 and 12 months after ECMO onset. METHODS: Multicenter, prospective study in patients who received ECMO for COVID-19 acute respiratory distress syndrome from March to June 2020 and survived hospital discharge. MEASUREMENTS AND MAIN RESULTS: Of 80 eligible patients, 62 were enrolled in seven French ICUs. ECMO and invasive mechanical ventilation duration were 18 (11–25) and 36 (27–62) days, respectively. All were alive, but only 19/50 (38%) returned to work and 13/42 (31%) had recovered a normal sex drive at 1 year. Pulmonary function tests were almost normal at 6 months, except for Dl(CO), which was still impaired at 12 months. Mental health, role-emotional, and role-physical were the most impaired domain compared with patients receiving ECMO who did not have COVID-19. One year after ICU admission, 19/43 (44%) patients had significant anxiety, 18/43 (42%) had depression symptoms, and 21/50 (42%) were at risk for post-traumatic stress disorders. CONCLUSIONS: Despite the partial recovery of the lung function tests at 1 year, the physical and psychological function of this population remains impaired. Based on the comparison with long-term follow-up of patients receiving ECMO who did not have COVID-19, poor mental and physical health may be more related to COVID-19 than to ECMO in itself, although this needs confirmation. |
format | Online Article Text |
id | pubmed-9893333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Thoracic Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-98933332023-02-06 One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome Chommeloux, Juliette Valentin, Simon Winiszewski, Hadrien Adda, Mélanie Pineton de Chambrun, Marc Moyon, Quentin Mathian, Alexis Capellier, Gilles Guervilly, Christophe Levy, Bruno Jaquet, Pierre Sonneville, Romain Voiriot, Guillaume Demoule, Alexandre Boussouar, Samia Painvin, Benoit Lebreton, Guillaume Combes, Alain Schmidt, Matthieu Am J Respir Crit Care Med Original Articles RATIONALE: Long-term outcomes of patients with coronavirus disease (COVID-19)–related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. OBJECTIVES: To assess physical examination, pulmonary function tests, anxiety, depression, post-traumatic stress disorder and quality of life at 6 and 12 months after ECMO onset. METHODS: Multicenter, prospective study in patients who received ECMO for COVID-19 acute respiratory distress syndrome from March to June 2020 and survived hospital discharge. MEASUREMENTS AND MAIN RESULTS: Of 80 eligible patients, 62 were enrolled in seven French ICUs. ECMO and invasive mechanical ventilation duration were 18 (11–25) and 36 (27–62) days, respectively. All were alive, but only 19/50 (38%) returned to work and 13/42 (31%) had recovered a normal sex drive at 1 year. Pulmonary function tests were almost normal at 6 months, except for Dl(CO), which was still impaired at 12 months. Mental health, role-emotional, and role-physical were the most impaired domain compared with patients receiving ECMO who did not have COVID-19. One year after ICU admission, 19/43 (44%) patients had significant anxiety, 18/43 (42%) had depression symptoms, and 21/50 (42%) were at risk for post-traumatic stress disorders. CONCLUSIONS: Despite the partial recovery of the lung function tests at 1 year, the physical and psychological function of this population remains impaired. Based on the comparison with long-term follow-up of patients receiving ECMO who did not have COVID-19, poor mental and physical health may be more related to COVID-19 than to ECMO in itself, although this needs confirmation. American Thoracic Society 2022-09-23 /pmc/articles/PMC9893333/ /pubmed/36150112 http://dx.doi.org/10.1164/rccm.202206-1145OC Text en Copyright © 2023 by the American Thoracic Society https://creativecommons.org/licenses/by-nc-nd/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . For commercial usage and reprints, please e-mail Diane Gern (dgern@thoracic.org). |
spellingShingle | Original Articles Chommeloux, Juliette Valentin, Simon Winiszewski, Hadrien Adda, Mélanie Pineton de Chambrun, Marc Moyon, Quentin Mathian, Alexis Capellier, Gilles Guervilly, Christophe Levy, Bruno Jaquet, Pierre Sonneville, Romain Voiriot, Guillaume Demoule, Alexandre Boussouar, Samia Painvin, Benoit Lebreton, Guillaume Combes, Alain Schmidt, Matthieu One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome |
title | One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome |
title_full | One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome |
title_fullStr | One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome |
title_full_unstemmed | One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome |
title_short | One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome |
title_sort | one-year mental and physical health assessment in survivors after extracorporeal membrane oxygenation for covid-19–related acute respiratory distress syndrome |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893333/ https://www.ncbi.nlm.nih.gov/pubmed/36150112 http://dx.doi.org/10.1164/rccm.202206-1145OC |
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