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One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome

RATIONALE: Long-term outcomes of patients with coronavirus disease (COVID-19)–related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. OBJECTIVES: To assess physical examination, pulmonary function tests, anxiety, depression, post-traumatic str...

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Autores principales: Chommeloux, Juliette, Valentin, Simon, Winiszewski, Hadrien, Adda, Mélanie, Pineton de Chambrun, Marc, Moyon, Quentin, Mathian, Alexis, Capellier, Gilles, Guervilly, Christophe, Levy, Bruno, Jaquet, Pierre, Sonneville, Romain, Voiriot, Guillaume, Demoule, Alexandre, Boussouar, Samia, Painvin, Benoit, Lebreton, Guillaume, Combes, Alain, Schmidt, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893333/
https://www.ncbi.nlm.nih.gov/pubmed/36150112
http://dx.doi.org/10.1164/rccm.202206-1145OC
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author Chommeloux, Juliette
Valentin, Simon
Winiszewski, Hadrien
Adda, Mélanie
Pineton de Chambrun, Marc
Moyon, Quentin
Mathian, Alexis
Capellier, Gilles
Guervilly, Christophe
Levy, Bruno
Jaquet, Pierre
Sonneville, Romain
Voiriot, Guillaume
Demoule, Alexandre
Boussouar, Samia
Painvin, Benoit
Lebreton, Guillaume
Combes, Alain
Schmidt, Matthieu
author_facet Chommeloux, Juliette
Valentin, Simon
Winiszewski, Hadrien
Adda, Mélanie
Pineton de Chambrun, Marc
Moyon, Quentin
Mathian, Alexis
Capellier, Gilles
Guervilly, Christophe
Levy, Bruno
Jaquet, Pierre
Sonneville, Romain
Voiriot, Guillaume
Demoule, Alexandre
Boussouar, Samia
Painvin, Benoit
Lebreton, Guillaume
Combes, Alain
Schmidt, Matthieu
author_sort Chommeloux, Juliette
collection PubMed
description RATIONALE: Long-term outcomes of patients with coronavirus disease (COVID-19)–related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. OBJECTIVES: To assess physical examination, pulmonary function tests, anxiety, depression, post-traumatic stress disorder and quality of life at 6 and 12 months after ECMO onset. METHODS: Multicenter, prospective study in patients who received ECMO for COVID-19 acute respiratory distress syndrome from March to June 2020 and survived hospital discharge. MEASUREMENTS AND MAIN RESULTS: Of 80 eligible patients, 62 were enrolled in seven French ICUs. ECMO and invasive mechanical ventilation duration were 18 (11–25) and 36 (27–62) days, respectively. All were alive, but only 19/50 (38%) returned to work and 13/42 (31%) had recovered a normal sex drive at 1 year. Pulmonary function tests were almost normal at 6 months, except for Dl(CO), which was still impaired at 12 months. Mental health, role-emotional, and role-physical were the most impaired domain compared with patients receiving ECMO who did not have COVID-19. One year after ICU admission, 19/43 (44%) patients had significant anxiety, 18/43 (42%) had depression symptoms, and 21/50 (42%) were at risk for post-traumatic stress disorders. CONCLUSIONS: Despite the partial recovery of the lung function tests at 1 year, the physical and psychological function of this population remains impaired. Based on the comparison with long-term follow-up of patients receiving ECMO who did not have COVID-19, poor mental and physical health may be more related to COVID-19 than to ECMO in itself, although this needs confirmation.
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spelling pubmed-98933332023-02-06 One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome Chommeloux, Juliette Valentin, Simon Winiszewski, Hadrien Adda, Mélanie Pineton de Chambrun, Marc Moyon, Quentin Mathian, Alexis Capellier, Gilles Guervilly, Christophe Levy, Bruno Jaquet, Pierre Sonneville, Romain Voiriot, Guillaume Demoule, Alexandre Boussouar, Samia Painvin, Benoit Lebreton, Guillaume Combes, Alain Schmidt, Matthieu Am J Respir Crit Care Med Original Articles RATIONALE: Long-term outcomes of patients with coronavirus disease (COVID-19)–related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. OBJECTIVES: To assess physical examination, pulmonary function tests, anxiety, depression, post-traumatic stress disorder and quality of life at 6 and 12 months after ECMO onset. METHODS: Multicenter, prospective study in patients who received ECMO for COVID-19 acute respiratory distress syndrome from March to June 2020 and survived hospital discharge. MEASUREMENTS AND MAIN RESULTS: Of 80 eligible patients, 62 were enrolled in seven French ICUs. ECMO and invasive mechanical ventilation duration were 18 (11–25) and 36 (27–62) days, respectively. All were alive, but only 19/50 (38%) returned to work and 13/42 (31%) had recovered a normal sex drive at 1 year. Pulmonary function tests were almost normal at 6 months, except for Dl(CO), which was still impaired at 12 months. Mental health, role-emotional, and role-physical were the most impaired domain compared with patients receiving ECMO who did not have COVID-19. One year after ICU admission, 19/43 (44%) patients had significant anxiety, 18/43 (42%) had depression symptoms, and 21/50 (42%) were at risk for post-traumatic stress disorders. CONCLUSIONS: Despite the partial recovery of the lung function tests at 1 year, the physical and psychological function of this population remains impaired. Based on the comparison with long-term follow-up of patients receiving ECMO who did not have COVID-19, poor mental and physical health may be more related to COVID-19 than to ECMO in itself, although this needs confirmation. American Thoracic Society 2022-09-23 /pmc/articles/PMC9893333/ /pubmed/36150112 http://dx.doi.org/10.1164/rccm.202206-1145OC Text en Copyright © 2023 by the American Thoracic Society https://creativecommons.org/licenses/by-nc-nd/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . For commercial usage and reprints, please e-mail Diane Gern (dgern@thoracic.org).
spellingShingle Original Articles
Chommeloux, Juliette
Valentin, Simon
Winiszewski, Hadrien
Adda, Mélanie
Pineton de Chambrun, Marc
Moyon, Quentin
Mathian, Alexis
Capellier, Gilles
Guervilly, Christophe
Levy, Bruno
Jaquet, Pierre
Sonneville, Romain
Voiriot, Guillaume
Demoule, Alexandre
Boussouar, Samia
Painvin, Benoit
Lebreton, Guillaume
Combes, Alain
Schmidt, Matthieu
One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
title One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
title_full One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
title_fullStr One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
title_full_unstemmed One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
title_short One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19–related Acute Respiratory Distress Syndrome
title_sort one-year mental and physical health assessment in survivors after extracorporeal membrane oxygenation for covid-19–related acute respiratory distress syndrome
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893333/
https://www.ncbi.nlm.nih.gov/pubmed/36150112
http://dx.doi.org/10.1164/rccm.202206-1145OC
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