Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation

In this issue of Structure, Wang et al. investigate the interplay between folded and disordered regions of the SARS-CoV-2 non-structural protein 1 (Nsp1) that promotes the suppression of host protein translation. Their investigation will lead to novel avenues to therapeutically target critical viral...

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Detalles Bibliográficos
Autores principales: Libich, David S., Baudin, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893522/
https://www.ncbi.nlm.nih.gov/pubmed/36736295
http://dx.doi.org/10.1016/j.str.2023.01.004
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author Libich, David S.
Baudin, Antoine
author_facet Libich, David S.
Baudin, Antoine
author_sort Libich, David S.
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description In this issue of Structure, Wang et al. investigate the interplay between folded and disordered regions of the SARS-CoV-2 non-structural protein 1 (Nsp1) that promotes the suppression of host protein translation. Their investigation will lead to novel avenues to therapeutically target critical viral functions necessary for host immune-response suppression.
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spelling pubmed-98935222023-02-02 Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation Libich, David S. Baudin, Antoine Structure Preview In this issue of Structure, Wang et al. investigate the interplay between folded and disordered regions of the SARS-CoV-2 non-structural protein 1 (Nsp1) that promotes the suppression of host protein translation. Their investigation will lead to novel avenues to therapeutically target critical viral functions necessary for host immune-response suppression. Elsevier Ltd. 2023-02-02 2023-02-02 /pmc/articles/PMC9893522/ /pubmed/36736295 http://dx.doi.org/10.1016/j.str.2023.01.004 Text en © 2023 Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Preview
Libich, David S.
Baudin, Antoine
Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation
title Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation
title_full Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation
title_fullStr Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation
title_full_unstemmed Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation
title_short Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation
title_sort order and disorder bound together in sars-cov-2 nsp1 suppress host translation
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893522/
https://www.ncbi.nlm.nih.gov/pubmed/36736295
http://dx.doi.org/10.1016/j.str.2023.01.004
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