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Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers
BACKGROUND: Proteins of the TGFβ family, which are largely studied as homodimers, are also known to form heterodimers with biological activity distinct from their component homodimers. For instance, heterodimers of bone morphogenetic proteins, including BMP2/BMP7, BMP2/BMP6, and BMP9/BMP10, among ot...
Autores principales: | Gipson, Gregory R., Nolan, Kristof, Kattamuri, Chandramohan, Kenny, Alan P., Agricola, Zachary, Edwards, Nicole A., Zinski, Joseph, Czepnik, Magdalena, Mullins, Mary C., Zorn, Aaron M., Thompson, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893541/ https://www.ncbi.nlm.nih.gov/pubmed/36726183 http://dx.doi.org/10.1186/s12915-023-01522-4 |
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