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Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers

BACKGROUND: Proteins of the TGFβ family, which are largely studied as homodimers, are also known to form heterodimers with biological activity distinct from their component homodimers. For instance, heterodimers of bone morphogenetic proteins, including BMP2/BMP7, BMP2/BMP6, and BMP9/BMP10, among ot...

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Detalles Bibliográficos
Autores principales: Gipson, Gregory R., Nolan, Kristof, Kattamuri, Chandramohan, Kenny, Alan P., Agricola, Zachary, Edwards, Nicole A., Zinski, Joseph, Czepnik, Magdalena, Mullins, Mary C., Zorn, Aaron M., Thompson, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893541/
https://www.ncbi.nlm.nih.gov/pubmed/36726183
http://dx.doi.org/10.1186/s12915-023-01522-4

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