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Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models

BACKGROUND: The majority of genes in the human genome is present in two copies but the expression levels of both alleles is not equal. Allelic imbalance is an aspect of gene expression relevant not only in the context of genetic variation, but also to understand the pathophysiology of genes implicat...

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Detalles Bibliográficos
Autores principales:	Joachimiak, Paweł, Ciesiołka, Adam, Kozłowska, Emilia, Świtoński, Paweł M., Figura, Grzegorz, Ciołak, Agata, Adamek, Grażyna, Surdyka, Magdalena, Kalinowska-Pośka, Żaneta, Figiel, Maciej, Caron, Nicholas S., Hayden, Michael R., Fiszer, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893648/ https://www.ncbi.nlm.nih.gov/pubmed/36726088 http://dx.doi.org/10.1186/s12915-023-01515-3

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