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Atorvastatin reduces contrast media-induced pyroptosis of renal tubular epithelial cells by inhibiting the TLR4/MyD88/NF-κB signaling pathway

BACKGROUND: Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of hospital-acquired renal failure. However, there is no effective treatment of CI-AKI, and its mechanism is unknown. Interestingly, atorvastatin has been reported to be effective in renal injury. Therefore, the...

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Detalles Bibliográficos
Autores principales: Yue, Rong-zheng, Li, Ya-juan, Su, Bai-hai, Li, Cong-jun, Zeng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893683/
https://www.ncbi.nlm.nih.gov/pubmed/36732683
http://dx.doi.org/10.1186/s12882-023-03066-9