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Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population

BACKGROUND: Despite advances in therapeutic management of patients with heart failure, there is still an increasing morbidity and mortality all over the world. In this study, we aimed to present the 3-year follow-up outcomes of patients included in the Journey HF-TR study in 2016 that has evaluated...

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Autores principales: Şabanoğlu, Cengiz, Sinan, Ümit Yaşar, Akboğa, Mehmet Kadri, Çoner, Ali, Gök, Gülay, Kocabaş, Umut, Bekar, Lütfü, Gazi, Emine, Cengiz, Mahir, Kılıç, Salih, İnanç, İbrahim Halil, Çakmak, Hüseyin Altuğ, Zoghi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish Society of Cardiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893707/
https://www.ncbi.nlm.nih.gov/pubmed/36680444
http://dx.doi.org/10.14744/AnatolJCardiol.2022.2171
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author Şabanoğlu, Cengiz
Sinan, Ümit Yaşar
Akboğa, Mehmet Kadri
Çoner, Ali
Gök, Gülay
Kocabaş, Umut
Bekar, Lütfü
Gazi, Emine
Cengiz, Mahir
Kılıç, Salih
İnanç, İbrahim Halil
Çakmak, Hüseyin Altuğ
Zoghi, Mehdi
author_facet Şabanoğlu, Cengiz
Sinan, Ümit Yaşar
Akboğa, Mehmet Kadri
Çoner, Ali
Gök, Gülay
Kocabaş, Umut
Bekar, Lütfü
Gazi, Emine
Cengiz, Mahir
Kılıç, Salih
İnanç, İbrahim Halil
Çakmak, Hüseyin Altuğ
Zoghi, Mehdi
author_sort Şabanoğlu, Cengiz
collection PubMed
description BACKGROUND: Despite advances in therapeutic management of patients with heart failure, there is still an increasing morbidity and mortality all over the world. In this study, we aimed to present the 3-year follow-up outcomes of patients included in the Journey HF-TR study in 2016 that has evaluated the clinical characteristics and management of patients with acute heart failure admitted to the hospital and present a national registry data. METHODS: The study was designed retrospectively between November 2016 and December 2019. Patient data included in the previously published Journey HF-TR study were used. Among 1606 patients, 1484 patients were included due to dropout of 122 patients due to inhospital death and due to exclusion of 173 due to incomplete data. The study included 1311 patients. Age, gender, concomitant chronic conditions, precipitating factors, New York Heart Association, and left ventricular ejection fraction factors were adjusted in the Cox regression analysis. RESULTS: During the 3-year follow-up period, the ratio of hospitalization and mortality was 70.5% and 52.1%, respectively. Common causes of mortality were acute decompensation of heart failure and acute coronary syndrome. Angiotensin receptor blockers, beta-blockers, statin, and sacubitril/valsartan were found to reduce mortality. Hospitalization due to acute decompensated heart failure, acute coronary syndrome, lung diseases, oncological diseases, and cerebrovascular diseases was associated with the increased risk of mortality. Implantation of cardiac devices also reduced the mortality. CONCLUSIONS: Despite advances in therapeutic management of patients with heart failure, our study demonstrated that the long-term mortality still is high. Much more efforts are needed to improve the inhospital and long-term survival of patients with chronic heart failure.
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spelling pubmed-98937072023-02-14 Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population Şabanoğlu, Cengiz Sinan, Ümit Yaşar Akboğa, Mehmet Kadri Çoner, Ali Gök, Gülay Kocabaş, Umut Bekar, Lütfü Gazi, Emine Cengiz, Mahir Kılıç, Salih İnanç, İbrahim Halil Çakmak, Hüseyin Altuğ Zoghi, Mehdi Anatol J Cardiol Original Investigation BACKGROUND: Despite advances in therapeutic management of patients with heart failure, there is still an increasing morbidity and mortality all over the world. In this study, we aimed to present the 3-year follow-up outcomes of patients included in the Journey HF-TR study in 2016 that has evaluated the clinical characteristics and management of patients with acute heart failure admitted to the hospital and present a national registry data. METHODS: The study was designed retrospectively between November 2016 and December 2019. Patient data included in the previously published Journey HF-TR study were used. Among 1606 patients, 1484 patients were included due to dropout of 122 patients due to inhospital death and due to exclusion of 173 due to incomplete data. The study included 1311 patients. Age, gender, concomitant chronic conditions, precipitating factors, New York Heart Association, and left ventricular ejection fraction factors were adjusted in the Cox regression analysis. RESULTS: During the 3-year follow-up period, the ratio of hospitalization and mortality was 70.5% and 52.1%, respectively. Common causes of mortality were acute decompensation of heart failure and acute coronary syndrome. Angiotensin receptor blockers, beta-blockers, statin, and sacubitril/valsartan were found to reduce mortality. Hospitalization due to acute decompensated heart failure, acute coronary syndrome, lung diseases, oncological diseases, and cerebrovascular diseases was associated with the increased risk of mortality. Implantation of cardiac devices also reduced the mortality. CONCLUSIONS: Despite advances in therapeutic management of patients with heart failure, our study demonstrated that the long-term mortality still is high. Much more efforts are needed to improve the inhospital and long-term survival of patients with chronic heart failure. Turkish Society of Cardiology 2023-01-01 /pmc/articles/PMC9893707/ /pubmed/36680444 http://dx.doi.org/10.14744/AnatolJCardiol.2022.2171 Text en 2023 authors https://creativecommons.org/licenses/by-nc/4.0/ Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Original Investigation
Şabanoğlu, Cengiz
Sinan, Ümit Yaşar
Akboğa, Mehmet Kadri
Çoner, Ali
Gök, Gülay
Kocabaş, Umut
Bekar, Lütfü
Gazi, Emine
Cengiz, Mahir
Kılıç, Salih
İnanç, İbrahim Halil
Çakmak, Hüseyin Altuğ
Zoghi, Mehdi
Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population
title Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population
title_full Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population
title_fullStr Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population
title_full_unstemmed Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population
title_short Long-Term Prognosis of Patients with Heart Failure: Follow-Up Results of Journey HF-TR Study Population
title_sort long-term prognosis of patients with heart failure: follow-up results of journey hf-tr study population
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893707/
https://www.ncbi.nlm.nih.gov/pubmed/36680444
http://dx.doi.org/10.14744/AnatolJCardiol.2022.2171
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