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Employing QbD strategies to assess the impact of cell viability and density on the primary recovery of monoclonal antibodies

Quality by Design (QbD) is one of the most important tools for the implementation of Process Analytical Technology (PAT) in biopharmaceutical production. For optimal characterization of a monoclonal antibody (mAb) upstream process a stepwise approach was implemented. The upstream was divided into th...

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Detalles Bibliográficos
Autores principales:	Wohlenberg, Ole Jacob, Kortmann, Carlotta, Meyer, Katharina V., Scheper, Thomas, Solle, Dörte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893750/ https://www.ncbi.nlm.nih.gov/pubmed/36751474 http://dx.doi.org/10.1002/elsc.202200056

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