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Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma

Less than 1.0% of malignant lymphomas are primary cardiac lymphoma (PCL), a rare malignant lymphoma. Due to its infrequency, the metabolic dynamics of the treatment have not been completely analyzed. A 62-year-old man who had been complaining of exertional dyspnea for a month arrived at our emergenc...

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Autores principales: Imataki, Osamu, Kubo, Hiroyuki, Fujita, Haruyuki, Uemura, Makiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894000/
https://www.ncbi.nlm.nih.gov/pubmed/36743878
http://dx.doi.org/10.1159/000527638
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author Imataki, Osamu
Kubo, Hiroyuki
Fujita, Haruyuki
Uemura, Makiko
author_facet Imataki, Osamu
Kubo, Hiroyuki
Fujita, Haruyuki
Uemura, Makiko
author_sort Imataki, Osamu
collection PubMed
description Less than 1.0% of malignant lymphomas are primary cardiac lymphoma (PCL), a rare malignant lymphoma. Due to its infrequency, the metabolic dynamics of the treatment have not been completely analyzed. A 62-year-old man who had been complaining of exertional dyspnea for a month arrived at our emergency room. He developed right cardiac failure as a result of a mass in the right atrium, according to a computed tomography (CT) scan. According to an echocardiogram, the mass was obstructing his blood flow and affecting how his heart worked. The lump was pathologically determined to be diffuse large B-cell lymphoma after he underwent urgent heart surgery. The lesion was only localized in the heart, according to a postoperative (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET)/CT scan, indicating that the disease was in clinical stage IE. An (18)F-FDG-PET/CT scan showed a thickness of the right atrial wall as residual disease despite the majority of the cardiac lymphomatous mass being removed during surgery; it also showed that the usual uptake of (18)F-FDG in healthy myocardium had diminished. Following chemotherapy, (18)F-FDG uptake recovered in the patient’s normal myocardium of the heart in remission. In conclusion, a sort of “metabolic steal phenomenon” that may be connected to PCL is the difference in uptake between tumor-involved and healthy myocardium.
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spelling pubmed-98940002023-02-03 Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma Imataki, Osamu Kubo, Hiroyuki Fujita, Haruyuki Uemura, Makiko Case Rep Oncol Case Report Less than 1.0% of malignant lymphomas are primary cardiac lymphoma (PCL), a rare malignant lymphoma. Due to its infrequency, the metabolic dynamics of the treatment have not been completely analyzed. A 62-year-old man who had been complaining of exertional dyspnea for a month arrived at our emergency room. He developed right cardiac failure as a result of a mass in the right atrium, according to a computed tomography (CT) scan. According to an echocardiogram, the mass was obstructing his blood flow and affecting how his heart worked. The lump was pathologically determined to be diffuse large B-cell lymphoma after he underwent urgent heart surgery. The lesion was only localized in the heart, according to a postoperative (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET)/CT scan, indicating that the disease was in clinical stage IE. An (18)F-FDG-PET/CT scan showed a thickness of the right atrial wall as residual disease despite the majority of the cardiac lymphomatous mass being removed during surgery; it also showed that the usual uptake of (18)F-FDG in healthy myocardium had diminished. Following chemotherapy, (18)F-FDG uptake recovered in the patient’s normal myocardium of the heart in remission. In conclusion, a sort of “metabolic steal phenomenon” that may be connected to PCL is the difference in uptake between tumor-involved and healthy myocardium. The Author(s). Published by S. Karger AG 2023-01-16 /pmc/articles/PMC9894000/ /pubmed/36743878 http://dx.doi.org/10.1159/000527638 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Imataki, Osamu
Kubo, Hiroyuki
Fujita, Haruyuki
Uemura, Makiko
Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma
title Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma
title_full Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma
title_fullStr Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma
title_full_unstemmed Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma
title_short Metabolic Steal of the Myocardium by Primary Cardiac Lymphoma
title_sort metabolic steal of the myocardium by primary cardiac lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894000/
https://www.ncbi.nlm.nih.gov/pubmed/36743878
http://dx.doi.org/10.1159/000527638
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