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Associations of polygenic risk scores for preeclampsia and blood pressure with hypertensive disorders of pregnancy

BACKGROUND: Preexisting hypertension increases risk for preeclampsia. We examined whether a generic blood pressure polygenic risk score (BP-PRS), compared with a preeclampsia-specific polygenic risk score (PE-PRS), could better predict hypertensive disorders of pregnancy. METHODS: Our study sample i...

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Detalles Bibliográficos
Autores principales: Nurkkala, Jouko, Kauko, Anni, FinnGen, Laivuori, Hannele, Saarela, Tanja, Tyrmi, Jaakko S., Vaura, Felix, Cheng, Susan, Bello, Natalie A., Aittokallio, Jenni, Niiranen, Teemu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894151/
https://www.ncbi.nlm.nih.gov/pubmed/36947680
http://dx.doi.org/10.1097/HJH.0000000000003336

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