Host variation in type I interferon signaling genes (MX1), C–C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size

Prior genomewide association studies have identified variation in major histocompatibility complex (MHC) class I alleles and C–C chemokine receptor type 5 gene (CCR5Δ32) as genetic predictors of viral control, especially in ‘elite’ controllers, individuals who remain virally suppressed in the absenc...

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Detalles Bibliográficos
Autores principales: Siegel, David A., Thanh, Cassandra, Wan, Eunice, Hoh, Rebecca, Hobbs, Kristen, Pan, Tony, Gibson, Erica A., Kroetz, Deanna L., Martin, Jeffrey, Hecht, Frederick, Pilcher, Christopher, Martin, Maureen, Carrington, Mary, Pillai, Satish, Busch, Michael P., Stone, Mars, Levy, Claire N., Huang, Meei-Li, Roychoudhury, Pavitra, Hladik, Florian, Jerome, Keith R., Kiem, Hans-Peter, Henrich, Timothy J., Deeks, Steven G., Lee, Sulggi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Epidemiology and Social
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894159/
https://www.ncbi.nlm.nih.gov/pubmed/36695358
http://dx.doi.org/10.1097/QAD.0000000000003428

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