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Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala

We report the effects of aspartame on anxiety-like behavior, neurotransmitter signaling and gene expression in the amygdala, a brain region associated with the regulation of anxiety and fear responses. C57BL/6 mice consumed drinking water containing 0.015% or 0.03% aspartame, a dose equivalent of 8...

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Detalles Bibliográficos
Autores principales: Jones, Sara K., McCarthy, Deirdre M., Vied, Cynthia, Stanwood, Gregg D., Schatschneider, Chris, Bhide, Pradeep G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894161/
https://www.ncbi.nlm.nih.gov/pubmed/36459641
http://dx.doi.org/10.1073/pnas.2213120119