The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription

Zika virus (ZIKV) targets the neural progenitor cells (NPCs) in brain during intrauterine infections and consequently causes severe neurological disorders, such as microcephaly in neonates. Although replicating in the cytoplasm, ZIKV dysregulates the expression of thousands of host genes, yet the de...

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Detalles Bibliográficos
Autores principales: Li, Ping, Wu, Junyu, Liu, Shujie, Lu, Ruiqing, Jiang, Hualian, Wang, Niu, Luo, Manhui, Guo, Liping, Xiao, Jingshu, Bu, Lang, Liu, Lihong, Xing, Fan, Peng, Hong, Li, Chunmei, Ma, Lan, Zhao, Bo, Zhou, Zhongwei, Guo, Deyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894162/
https://www.ncbi.nlm.nih.gov/pubmed/36442102
http://dx.doi.org/10.1073/pnas.2205013119

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