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PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets

Rhabdomyosarcoma (RMS) is an aggressive pediatric soft-tissue cancer with features of skeletal muscle. Because of poor survival of RMS patients and severe long-term side effects of RMS therapies, alternative RMS therapies are urgently needed. Here we show that the prospero-related homeobox 1 (PROX1)...

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Detalles Bibliográficos
Autores principales: Gizaw, Nebeyu Yosef, Kallio, Pauliina, Punger, Tatjana, Gucciardo, Erika, Haglund, Caj, Böhling, Tom, Lehti, Kaisa, Sampo, Mika, Alitalo, Kari, Kivelä, Riikka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894179/
https://www.ncbi.nlm.nih.gov/pubmed/36459642
http://dx.doi.org/10.1073/pnas.2116220119

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