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PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets
Rhabdomyosarcoma (RMS) is an aggressive pediatric soft-tissue cancer with features of skeletal muscle. Because of poor survival of RMS patients and severe long-term side effects of RMS therapies, alternative RMS therapies are urgently needed. Here we show that the prospero-related homeobox 1 (PROX1)...
Autores principales: | Gizaw, Nebeyu Yosef, Kallio, Pauliina, Punger, Tatjana, Gucciardo, Erika, Haglund, Caj, Böhling, Tom, Lehti, Kaisa, Sampo, Mika, Alitalo, Kari, Kivelä, Riikka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894179/ https://www.ncbi.nlm.nih.gov/pubmed/36459642 http://dx.doi.org/10.1073/pnas.2116220119 |
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