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Moderate activity of RNA chaperone maximizes the yield of self-spliced pre-RNA in vivo

CYT-19 is a DEAD-box protein whose adenosine-triphosphate (ATP)-dependent helicase activity facilitates the folding of group I introns in precursor RNA (pre-RNA) of Neurospora crassa (N. crassa). In the process, they consume a substantial amount of ATP. While much of the mechanistic insight into CYT...

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Detalles Bibliográficos
Autores principales: Song, Yonghyun, Thirumalai, D., Hyeon, Changbong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894238/
https://www.ncbi.nlm.nih.gov/pubmed/36442111
http://dx.doi.org/10.1073/pnas.2209422119