Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia

The current classification of acute myeloid leukemia (AML) relies largely on genomic alterations. Robust identification of clinically and biologically relevant molecular subtypes from nongenomic high-throughput sequencing data remains challenging. We established the largest multicenter AML cohort (n...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Yan, Li, Jian-Feng, Zhu, Yong-Mei, Lin, Xiang-Jie, Wen, Li-Jun, Zhang, Fan, Zhang, Yu-Liang, Zhao, Ming, Fang, Hai, Wang, Sheng-Yue, Lin, Xiao-Jing, Qiao, Niu, Yin, Wei, Zhang, Jia-Nan, Dai, Yu-Ting, Jiang, Lu, Sun, Xiao-Jian, Xu, Yi, Zhang, Tong-Tong, Chen, Su-Ning, Zhu, Hong-Hu, Chen, Zhu, Jin, Jie, Wu, De-Pei, Shen, Yang, Chen, Sai-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894241/
https://www.ncbi.nlm.nih.gov/pubmed/36442087
http://dx.doi.org/10.1073/pnas.2211429119

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