The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining

The protooncoprotein N-Myc, which is overexpressed in approximately 25% of neuroblastomas as the consequence of MYCN gene amplification, has long been postulated to regulate DNA double-strand break (DSB) repair in neuroblastoma cells, but experimental evidence of this function is presently scant. He...

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Detalles Bibliográficos
Autores principales: Wang, Pei Lin, Teng, Liu, Feng, Yu Chen, Yue, Yi Meng, Han, Man Man, Yan, Qianqian, Ye, Kaihong, Tang, Cai Xia, Zhang, Sheng Nan, Fei Qi, Teng, Zhao, Xiao Hong, La, Ting, Zhang, Yuan Yuan, Li, Jin Ming, Hu, Bin, Xu, Dengfei, Cang, Shundong, Wang, Li, Jin, Lei, Thorne, Rick F., Zhang, Yuwei, Liu, Tao, Zhang, Xu Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894261/
https://www.ncbi.nlm.nih.gov/pubmed/36445966
http://dx.doi.org/10.1073/pnas.2208904119

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