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Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance

We derive a simple asymptotic approximation for the long-run case fatality rate of COVID-19 (alpha and delta variants) and show that these estimations are highly correlated to the interaction between US State median age and projected US unemployment rate (Adj. r(2) = 60%). We contrast this to the hi...

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Autores principales: Griffin, Christopher, Block, Ray, Silverman, Justin D., Croad, Jason, Lennon, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894486/
https://www.ncbi.nlm.nih.gov/pubmed/36730260
http://dx.doi.org/10.1371/journal.pone.0274470
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author Griffin, Christopher
Block, Ray
Silverman, Justin D.
Croad, Jason
Lennon, Robert P.
author_facet Griffin, Christopher
Block, Ray
Silverman, Justin D.
Croad, Jason
Lennon, Robert P.
author_sort Griffin, Christopher
collection PubMed
description We derive a simple asymptotic approximation for the long-run case fatality rate of COVID-19 (alpha and delta variants) and show that these estimations are highly correlated to the interaction between US State median age and projected US unemployment rate (Adj. r(2) = 60%). We contrast this to the high level of correlation between point (instantaneous) estimates of per state case fatality rates and the interaction of median age, population density and current unemployment rates (Adj. r(2) = 50.2%). To determine whether this is caused by a “race effect,” we then analyze unemployment, race, median age and population density across US states and show that adding the interaction of African American population and unemployment explains 53.5% of the variance in COVID case fatality rates for the alpha and delta variants when considering instantaneous case fatality rate. Interestingly, when the asymptotic case fatality rate is used, the dependence on the African American population disappears, which is consistent with the fact that in the long-run COVID does not discriminate on race, but may discriminate on access to medical care which is highly correlated to employment in the US. The results provide further evidence of the impact inequality can have on case fatality rates in COVID-19 and the impact complex social, health and economic factors can have on patient survival.
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spelling pubmed-98944862023-02-03 Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance Griffin, Christopher Block, Ray Silverman, Justin D. Croad, Jason Lennon, Robert P. PLoS One Research Article We derive a simple asymptotic approximation for the long-run case fatality rate of COVID-19 (alpha and delta variants) and show that these estimations are highly correlated to the interaction between US State median age and projected US unemployment rate (Adj. r(2) = 60%). We contrast this to the high level of correlation between point (instantaneous) estimates of per state case fatality rates and the interaction of median age, population density and current unemployment rates (Adj. r(2) = 50.2%). To determine whether this is caused by a “race effect,” we then analyze unemployment, race, median age and population density across US states and show that adding the interaction of African American population and unemployment explains 53.5% of the variance in COVID case fatality rates for the alpha and delta variants when considering instantaneous case fatality rate. Interestingly, when the asymptotic case fatality rate is used, the dependence on the African American population disappears, which is consistent with the fact that in the long-run COVID does not discriminate on race, but may discriminate on access to medical care which is highly correlated to employment in the US. The results provide further evidence of the impact inequality can have on case fatality rates in COVID-19 and the impact complex social, health and economic factors can have on patient survival. Public Library of Science 2023-02-02 /pmc/articles/PMC9894486/ /pubmed/36730260 http://dx.doi.org/10.1371/journal.pone.0274470 Text en © 2023 Griffin et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Griffin, Christopher
Block, Ray
Silverman, Justin D.
Croad, Jason
Lennon, Robert P.
Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance
title Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance
title_full Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance
title_fullStr Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance
title_full_unstemmed Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance
title_short Race, employment, and the pandemic: An exploration of covariate explanations of COVID-19 case fatality rate variance
title_sort race, employment, and the pandemic: an exploration of covariate explanations of covid-19 case fatality rate variance
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894486/
https://www.ncbi.nlm.nih.gov/pubmed/36730260
http://dx.doi.org/10.1371/journal.pone.0274470
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