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In silico investigation of cytochrome bc1 molecular inhibition mechanism against Trypanosoma cruzi
Chagas’ disease is a neglected tropical disease caused by the kinetoplastid protozoan Trypanosoma cruzi. The only therapies are the nitroheterocyclic chemicals nifurtimox and benznidazole that cause various adverse effects. The need to create safe and effective medications to improve medical care re...
Autores principales: | Muscat, Stefano, Grasso, Gianvito, Scapozza, Leonardo, Danani, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894551/ https://www.ncbi.nlm.nih.gov/pubmed/36689459 http://dx.doi.org/10.1371/journal.pntd.0010545 |
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