Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine

Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of pediatric AML by screening myeloblast sensitivity...

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Detalles Bibliográficos
Autores principales: Wang, Han, Chan, Kathy Yuen Yee, Cheng, Chi Keung, Ng, Margaret H.L., Lee, Po Yi, Cheng, Frankie Wai Tsoi, Lam, Grace Kee See, Chow, Tin Wai, Ha, Shau Yin, Chiang, Alan K.S., Leung, Wing Hang, Leung, Anskar Y.H., Wang, Chi Chiu, Zhang, Tao, Zhang, Xiao-Bing, So, Chi Chiu, Yuen, Yuet Ping, Sun, Qiwei, Zhang, Chi, Xu, Yaqun, Cheung, John Tak Kit, Ng, Wing Hei, Tang, Patrick Ming-Kuen, Kang, Wei, To, Ka-Fai, Lee, Wayne Yuk Wai, Wong, Raymond S.M., Poon, Ellen Ngar Yun, Zhao, Qi, Huang, Junbin, Chen, Chun, Yuen, Patrick Man Pan, Li, Chi-kong, Leung, Alex Wing Kwan, Leung, Kam Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894568/
https://www.ncbi.nlm.nih.gov/pubmed/35960210
http://dx.doi.org/10.1158/2643-3230.BCD-22-0011

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