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An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge

Hereditary neuropathy with liability to pressure palsy (HNPP) is a genetic condition in which individuals develop recurrent nerve palsies due to nerve injury at susceptible anatomic sites. Because of its rarity, other diseases usually appear high in the differential list when the clinical presentati...

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Detalles Bibliográficos
Autores principales: Saurabh, Kumar, Ahmad, Reyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894645/
https://www.ncbi.nlm.nih.gov/pubmed/36741649
http://dx.doi.org/10.7759/cureus.33306
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author Saurabh, Kumar
Ahmad, Reyaz
author_facet Saurabh, Kumar
Ahmad, Reyaz
author_sort Saurabh, Kumar
collection PubMed
description Hereditary neuropathy with liability to pressure palsy (HNPP) is a genetic condition in which individuals develop recurrent nerve palsies due to nerve injury at susceptible anatomic sites. Because of its rarity, other diseases usually appear high in the differential list when the clinical presentation is suggestive. Here, we describe a case of HNPP initially thought of as radiculopathy and focal chronic inflammatory demyelinating polyneuropathy (CIDP). Only on close clinical examination, supportive electrodiagnostic tests, and recurrence with typical history, a diagnosis of HNPP was suspected and later confirmed by a genetic test.
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spelling pubmed-98946452023-02-03 An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge Saurabh, Kumar Ahmad, Reyaz Cureus Internal Medicine Hereditary neuropathy with liability to pressure palsy (HNPP) is a genetic condition in which individuals develop recurrent nerve palsies due to nerve injury at susceptible anatomic sites. Because of its rarity, other diseases usually appear high in the differential list when the clinical presentation is suggestive. Here, we describe a case of HNPP initially thought of as radiculopathy and focal chronic inflammatory demyelinating polyneuropathy (CIDP). Only on close clinical examination, supportive electrodiagnostic tests, and recurrence with typical history, a diagnosis of HNPP was suspected and later confirmed by a genetic test. Cureus 2023-01-03 /pmc/articles/PMC9894645/ /pubmed/36741649 http://dx.doi.org/10.7759/cureus.33306 Text en Copyright © 2023, Saurabh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Saurabh, Kumar
Ahmad, Reyaz
An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
title An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
title_full An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
title_fullStr An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
title_full_unstemmed An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
title_short An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
title_sort unusual case of hereditary neuropathy with liability to pressure palsy: a diagnostic challenge
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894645/
https://www.ncbi.nlm.nih.gov/pubmed/36741649
http://dx.doi.org/10.7759/cureus.33306
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