HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC

The development of an effective vaccine to protect against HIV acquisition will be greatly bolstered by in-depth understanding of the innate and adaptive responses to vaccination. We report here that the efficacy of DNA/ALVAC/gp120/alum vaccines, based on V2-specific antibodies mediating apoptosis o...

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Detalles Bibliográficos
Autores principales: Bissa, Massimiliano, Kim, Sohyoung, Galli, Veronica, Fourati, Slim, Sarkis, Sarkis, Arakelyan, Anush, de Castro, Isabela Silva, Rahman, Mohammad Arif, Fujiwara, Saori, Vaccari, Monica, Tomalka, Jeffrey A., Stamos, James D., Schifanella, Luca, Gorini, Giacomo, Moles, Ramona, Gutowska, Anna, Ferrari, Guido, Lobanov, Alexei, Montefiori, David C., Nelson, George W., Cam, Margaret C., Chakhtoura, Marita, Haddad, Elias K., Doster, Melvin N., McKinnon, Katherine, Brown, Sophia, Venzon, David J., Choo-Wosoba, Hyoyoung, Breed, Matthew W., Killoran, Kristin E., Kramer, Joshua, Margolis, Leonid, Sekaly, Rafick P., Hager, Gordon L., Franchini, Genoveffa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894672/
https://www.ncbi.nlm.nih.gov/pubmed/36732510
http://dx.doi.org/10.1038/s41467-023-36109-8

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