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Effects of hydroxychloroquine on atrial electrophysiology in in silico wild-type and PITX2(+/-) atrial cardiomyocytes

BACKGROUND: Hydroxychloroquine (HCQ) is commonly used in the treatment of autoimmune diseases and increases the risk of QT interval prolongation. However, it is unclear how HCQ affects atrial electrophysiology and the risk of atrial fibrillation (AF). METHODS: We quantitatively examined the potentia...

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Detalles Bibliográficos
Autor principal: Song, Euijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894744/
https://www.ncbi.nlm.nih.gov/pubmed/36732468
http://dx.doi.org/10.1007/s00059-023-05162-w