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CD8(+) lymphocytes do not impact SIV reservoir establishment under ART

Persistence of the human immunodeficiency virus type-1 (HIV-1) latent reservoir in infected individuals remains a problem despite fully suppressive antiretroviral therapy (ART). While reservoir formation begins during acute infection, the mechanisms responsible for its establishment remain unclear....

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Detalles Bibliográficos
Autores principales: Statzu, Maura, Jin, Wang, Fray, Emily J., Wong, Andrew Kam Ho, Kumar, Mithra R., Ferrer, Elizabeth, Docken, Steffen S., Pinkevych, Mykola, McBrien, Julia B., Fennessey, Christine M., Keele, Brandon F., Liang, Shan, Harper, Justin L., Mutascio, Simona, Franchitti, Lavinia, Wang, Hong, Cicetti, Davide, Bosinger, Steven E., Carnathan, Diane G., Vanderford, Thomas H., Margolis, David M., Garcia-Martinez, J. Victor, Chahroudi, Ann, Paiardini, Mirko, Siliciano, Janet, Davenport, Miles P., Kulpa, Deanna A., Siliciano, Robert S., Silvestri, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894752/
https://www.ncbi.nlm.nih.gov/pubmed/36690860
http://dx.doi.org/10.1038/s41564-022-01311-9

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