Differential serum microRNAs in premotor LRRK2 G2019S carriers from Parkinson’s disease

The LRRK2 G2019S pathogenic mutation causes LRRK2-associated Parkinson’s disease (L2PD) with incomplete penetrance. LRRK2 non-manifesting carriers (L2NMC) are at PD high risk but predicting pheno-conversion is challenging given the lack of progression biomarkers. To investigate novel biomarkers for...

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Detalles Bibliográficos
Autores principales: Soto, Marta, Fernández, Manel, Bravo, Paloma, Lahoz, Sara, Garrido, Alicia, Sánchez-Rodríguez, Antonio, Rivera-Sánchez, María, Sierra, María, Melón, Paula, Roig-García, Ana, Naito, Anna, Casey, Bradford, Camps, Jordi, Tolosa, Eduardo, Martí, María-José, Infante, Jon, Ezquerra, Mario, Fernández-Santiago, Rubén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894906/
https://www.ncbi.nlm.nih.gov/pubmed/36732514
http://dx.doi.org/10.1038/s41531-023-00451-x

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