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Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox

Response inhibition is essential for terminating inappropriate actions and, in some cases, may be required selectively. Selective stopping can be investigated with multicomponent anticipatory or stop-signal response inhibition paradigms. Here we provide a freely available open-source Selective Stopp...

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Autores principales: Wadsley, Corey G., Cirillo, John, Nieuwenhuys, Arne, Byblow, Winston D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894981/
https://www.ncbi.nlm.nih.gov/pubmed/36635589
http://dx.doi.org/10.1007/s00221-022-06539-9
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author Wadsley, Corey G.
Cirillo, John
Nieuwenhuys, Arne
Byblow, Winston D.
author_facet Wadsley, Corey G.
Cirillo, John
Nieuwenhuys, Arne
Byblow, Winston D.
author_sort Wadsley, Corey G.
collection PubMed
description Response inhibition is essential for terminating inappropriate actions and, in some cases, may be required selectively. Selective stopping can be investigated with multicomponent anticipatory or stop-signal response inhibition paradigms. Here we provide a freely available open-source Selective Stopping Toolbox (SeleST) to investigate selective stopping using either anticipatory or stop-signal task variants. This study aimed to evaluate selective stopping between the anticipatory and stop-signal variants using SeleST and provide guidance to researchers for future use. Forty healthy human participants performed bimanual anticipatory response inhibition and stop-signal tasks in SeleST. Responses were more variable and slowed to a greater extent during the stop-signal than in the anticipatory paradigm. However, the stop-signal paradigm better conformed to the assumption of the independent race model of response inhibition. The expected response delay during selective stop trials was present in both variants. These findings indicate that selective stopping can successfully be investigated with either anticipatory or stop-signal paradigms in SeleST. We propose that the anticipatory paradigm should be used when strict control of response times is desired, while the stop-signal paradigm should be used when it is desired to estimate stop-signal reaction time with the independent race model. Importantly, the dual functionality of SeleST allows researchers flexibility in paradigm selection when investigating selective stopping.
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spelling pubmed-98949812023-02-04 Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox Wadsley, Corey G. Cirillo, John Nieuwenhuys, Arne Byblow, Winston D. Exp Brain Res Research Article Response inhibition is essential for terminating inappropriate actions and, in some cases, may be required selectively. Selective stopping can be investigated with multicomponent anticipatory or stop-signal response inhibition paradigms. Here we provide a freely available open-source Selective Stopping Toolbox (SeleST) to investigate selective stopping using either anticipatory or stop-signal task variants. This study aimed to evaluate selective stopping between the anticipatory and stop-signal variants using SeleST and provide guidance to researchers for future use. Forty healthy human participants performed bimanual anticipatory response inhibition and stop-signal tasks in SeleST. Responses were more variable and slowed to a greater extent during the stop-signal than in the anticipatory paradigm. However, the stop-signal paradigm better conformed to the assumption of the independent race model of response inhibition. The expected response delay during selective stop trials was present in both variants. These findings indicate that selective stopping can successfully be investigated with either anticipatory or stop-signal paradigms in SeleST. We propose that the anticipatory paradigm should be used when strict control of response times is desired, while the stop-signal paradigm should be used when it is desired to estimate stop-signal reaction time with the independent race model. Importantly, the dual functionality of SeleST allows researchers flexibility in paradigm selection when investigating selective stopping. Springer Berlin Heidelberg 2023-01-13 2023 /pmc/articles/PMC9894981/ /pubmed/36635589 http://dx.doi.org/10.1007/s00221-022-06539-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Wadsley, Corey G.
Cirillo, John
Nieuwenhuys, Arne
Byblow, Winston D.
Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
title Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
title_full Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
title_fullStr Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
title_full_unstemmed Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
title_short Comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
title_sort comparing anticipatory and stop-signal response inhibition with a novel, open-source selective stopping toolbox
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894981/
https://www.ncbi.nlm.nih.gov/pubmed/36635589
http://dx.doi.org/10.1007/s00221-022-06539-9
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