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Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration

C-X-C chemokine receptor 4 (CXCR4) is widely overexpressed in various types of cancer and is involved in several cancer phenotypes including tumor growth, survival, and metastasis. The roles of histamine and histamine receptor H1 (HRH1) in cancer pathogenesis remain controversial. Here, we show that...

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Detalles Bibliográficos
Autores principales: Park, Chulo, Lee, Jin-Woo, Kim, Kiheon, Seen, Dong-Seung, Jeong, Jae-Yeon, Huh, Won-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895059/
https://www.ncbi.nlm.nih.gov/pubmed/36732336
http://dx.doi.org/10.1038/s41598-023-28531-1