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A novel variant of NR5A1, p.R350W implicates potential interactions with unknown co-factors or ligands
INTRODUCTION: NR5A1 and NR5A2 belong to an orphan nuclear receptor group, and approximately 60% of their amino acid sequences are conserved. Transcriptional regulation of NR5A receptors depends on interactions with co-factors or unidentified ligands. PURPOSE AND METHODS: We employed in vitro and in...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895113/ https://www.ncbi.nlm.nih.gov/pubmed/36743925 http://dx.doi.org/10.3389/fendo.2022.1033074 |