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Augmentation of IFN-γ by bone marrow derived immune cells in the presence of severe suppression of IFN-γ in gingivae induced by zoledronic acid and denosumab in Hu-BLT mice model of ONJ

INTRODUCTION: The potential mechanisms governing drug induced osteonecrosis of the jaw (ONJ) is not well understood, and is one of the objectives of this study. Thus, we tested the release of IFN-γ within different immune compartments including bone marrow and gingivae upon treatment with zoledronic...

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Detalles Bibliográficos
Autores principales: Kaur, Kawaljit, Sun, Yujie, Kanayama, Keiichi, Morinaga, Kenzo, Hokugo, Akishige, Nishimura, Ichiro, Jewett, Anahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895394/
https://www.ncbi.nlm.nih.gov/pubmed/36742414
http://dx.doi.org/10.3389/fendo.2023.1111627

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