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Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion culture strategies

The perfusion medium is critical in maintaining high cell concentration in cultures for the production of monoclonal antibody by Chinese hamster ovary cells. In this study, the effects of perfusion culture strategies when using different media on the process stability, product titer, and product qua...

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Detalles Bibliográficos
Autores principales:	Liang, Kexue, Luo, Hongzhen, Li, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895834/ https://www.ncbi.nlm.nih.gov/pubmed/36741761 http://dx.doi.org/10.3389/fbioe.2023.1112349

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