Cargando…

A Preliminary Study of Frequency and Clinical Relevance of Cytotoxic Peripheral CD4 and CD8 T Cells in Patients with Anti-MDA5 Positive Dermatomyositis

OBJECTIVES: Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5(+)DM) is an autoimmune disease frequently accompanied by rapidly progressive interstitial lung disease (RP-ILD) with high mortality. T cells are implicated in the pathogenesis of MDA5(+)DM and this study aims...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Fengyun, Jiang, Shan, Zhang, Jiamin, Fu, Qiong, Zhang, Xiaoming, Ye, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895870/ https://www.ncbi.nlm.nih.gov/pubmed/36788974 http://dx.doi.org/10.2478/rir-2022-0022

Ejemplares similares

Hypomyopathic Dermatomyositis Presenting with Idiopathic CD4 T-lymphocytopenia and Delayed Anti-MDA5 Positivity
por: Mijares, Maria C, et al.
Publicado: (2019)

Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications
por: Ye, Yan, et al.
Publicado: (2022)

Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis
por: Li, Wenli, et al.
Publicado: (2021)

Editorial: Anti-MDA5-Positive Dermatomyositis
por: Gono, Takahisa, et al.
Publicado: (2022)

Subcutaneous Calcinosis in a Patient with Anti-MDA5 Positive Dermatomyositis
por: Hou, Ruihong, et al.
Publicado: (2021)

7. Anti-MDA5 associated dermatomyositis
por: Laverty, Ursula, et al.
Publicado: (2019)

Seasonal Effect on Disease Onset and Presentation in Anti-MDA5 Positive Dermatomyositis
por: So, Ho, et al.
Publicado: (2022)

Treatment of MDA5-positive dermatomyositis complicated by gangrenous cholecystitis with tofacitinib
por: Luo, Man, et al.
Publicado: (2022)

Clinical Features of Dermatomyositis/Polymyositis with Anti-MDA5 Antibody Positivity
por: Chen, Qiuhe, et al.
Publicado: (2022)

Characteristics and prognostic implications of peripheral blood lymphocyte subsets in patients with anti-MDA5 antibody positive dermatomyositis-interstitial lung disease
por: Ren, Fang-Ping, et al.
Publicado: (2023)

Pneumomediastinum in MDA5-associated clinically amyopathic dermatomyositis
por: Kotsiou, Ourania S., et al.
Publicado: (2017)

Therapiealternativen bei amyopathischer MDA5-positiver Dermatomyositis
por: Schumacher, Falk, et al.
Publicado: (2023)

Soluble CD206 levels correlate with disease deterioration and predict prognosis of anti‐MDA5 antibody‐positive dermatomyositis related interstitial lung disease
por: Li, Yan, et al.
Publicado: (2023)

Neutrophil-to-lymphocyte ratio is a predictive marker for anti-MDA5 positive dermatomyositis
por: Liu, Tao, et al.
Publicado: (2022)

Cd8 Expression up to the Double-Positive CD3(Low/Intermediate) Stage of Thymic Differentiation Is Sufficient for Development of Peripheral Functional Cytotoxic T Lymphocytes
por: Zhang, X.-L., et al.
Publicado: (2001)

MDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentations
por: Parronchi, Paola, et al.
Publicado: (2015)

Anti-MDA5 antibody-positive dermatomyositis presenting as unilateral eyelid edema
por: Chen, Lauren, et al.
Publicado: (2020)

On the Nose: Anti-MDA-5 Dermatomyositis Manifesting as Perinasal Swelling
por: Molina, Emily, et al.
Publicado: (2022)

Type I interferon score is associated with the severity and poor prognosis in anti-MDA5 antibody-positive dermatomyositis patients
por: Qian, Jinjing, et al.
Publicado: (2023)

Cd8(+) but Not Cd8(−) Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo
por: den Haan, Joke M.M., et al.
Publicado: (2000)

Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis
por: Schirmer, Michael, et al.
Publicado: (2002)

Macrophage activation syndrome in MDA5 antibody-positive dermatomyositis and COVID-19 infection
por: Keshtkarjahromi, Marzieh, et al.
Publicado: (2021)

Cytotoxic CD161(−)CD8(+) T(EMRA) cells contribute to the pathogenesis of systemic lupus erythematosus
por: Xiong, Hui, et al.
Publicado: (2023)

CD100 modulates cytotoxicity of CD8(+) T cells in patients with acute myocardial infarction
por: Li, Yan, et al.
Publicado: (2021)

CD3(+)T, CD4(+)T, CD8(+)T, and CD4(+)T/CD8(+)T Ratio and Quantity of γδT Cells in Peripheral Blood of HIV-Infected/AIDS Patients and Its Clinical Significance
por: Zhao, Nange, et al.
Publicado: (2021)

Anti-MDA5 Amyopathic Dermatomyositis—A Diagnostic and Therapeutic Challenge
por: Bobirca, Anca, et al.
Publicado: (2022)

Elevated peripheral blood B lymphocytes and CD3(+)CD4(−)CD8(−) T lymphocytes in patients with non-small cell lung cancer: A preliminary study on peripheral immune profile
por: Liang, Hailong, et al.
Publicado: (2018)

The Significance of Tumor Necrosis Factor Receptor Type II in CD8(+) Regulatory T Cells and CD8(+) Effector T Cells
por: Ye, Lin-Lin, et al.
Publicado: (2018)

Management of MDA-5 antibody-positive dermatomyositis with interstitial lung disease—an Auckland case series
por: Dick, Michael, et al.
Publicado: (2021)

Cutaneous Features of Anti-MDA-5 Antibody-Positive Amyopathic Dermatomyositis in a Sudanese Patient
por: Alqahtani, Nouf, et al.
Publicado: (2021)

Mechanic’s Hand Heralding Relapse in an Indian Adolescent with Anti-MDA5 Positive Juvenile Dermatomyositis
por: Ganatra, Keya, et al.
Publicado: (2022)

Efficacy and safety of dose escalation of tofacitinib in refractory anti-MDA5 antibody-positive dermatomyositis
por: Ida, Tomoaki, et al.
Publicado: (2023)

Different Multivariable Risk Factors for Rapid Progressive Interstitial Lung Disease in Anti-MDA5 Positive Dermatomyositis and Anti-Synthetase Syndrome
por: Zuo, Yu, et al.
Publicado: (2022)

Transcriptomic profiling and longitudinal study reveal the relationship of anti-MDA5 titer and type I IFN signature in MDA5+ dermatomyositis
por: Wang, Yan, et al.
Publicado: (2023)

High incidence and mortality of Pneumocystis jirovecii infection in anti-MDA5-antibody-positive dermatomyositis: experience from a single center
por: Huang, Linlin, et al.
Publicado: (2021)

Prevalence, clinical relevance and characterization of circulating cytotoxic CD4(+)CD28(- )T cells in ankylosing spondylitis
por: Duftner, Christina, et al.
Publicado: (2003)

αβ-Double Negative CD4/CD8 (CD56) T cell (DNTs) in metastatic melanoma: basal frequency and behaviour during Ipilimumab treatment. Preliminary evaluations
por: De Tullio, Giacoma, et al.
Publicado: (2015)

Clinical Relevance of CD4 Cytotoxic T Cells in High-Risk Neuroblastoma
por: Tang, Xao X., et al.
Publicado: (2021)

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes
por: Kessler, Benedikt, et al.
Publicado: (1997)

NFATc1 controls the cytotoxicity of CD8(+) T cells
por: Klein-Hessling, Stefan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_b6qus9qdrh5aidr4feeirmi07f